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ORGANIC SYNTHESIS VIA EXAMINATION OF
SELECTED NATURAL PRODUCTS
by David J Hart (The Ohio State University, USA)
600pp
978-981-4313-70-4: US$112 / £77 US$84 /
£57.75
Powerpoint
Slides (25,756k)
Index
(358k)
This book is written for advanced graduate and undergraduate
students to expose them to a variety of strategies for the synthesis of
organic compounds. This is done largely within the context of natural
products synthesis, but some unnatural products synthesis is also
included. Multiple approaches to each group of synthesis targets are
presented, and the approaches are compared with one another with an eye
on similarities and differences. General problems in organic synthesis
(for example, strategies for the preparation of 6-membered rings and
5-membered rings, the importance of oxidation state, the problem of
acyclic diastereoselectivity, the problem of controlling absolute
stereochemistry, the importance of functional group relationships) are
introduced early in the book and revisited throughout the text within
the context of a variety of structurally unrelated natural products.
The book provides readers with a somewhat historical overview
of organic and natural products chemistry, and spans synthetic
methodology that dates from the 1940's to the present time. It is
written in a style that readers will find entertaining at times. It
also contains lots of useful references with complete titles provided.
Contents:
- Notes from the Author and Introduction
- Steroids
- Prostaglandins
- Pyrrolizidine Alkaloids
- Juvabione
- Difunctional Relationships
- Unnatural Products
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- Alkaloids and the Mannich Reaction
- Dart-Poison Alkaloids
- Morphine
- Cecropia Juvenile Hormone
- Lasonolide A
- Calcymycin
- Erythromycin A Aglycone
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